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EAU 2026 | Intravesical erdafitinib in BCG-unresponsive NMIBC: local efficacy, minimal systemic exposure

Antoni Vilaseca, MD, Hospital Clínic de Barcelona, Barcelona, Spain, discusses the potential of intravesical erdafitinib for treating high-risk non-muscle-invasive bladder cancer, highlighting its localized exposure and reduced systemic side effects. Dr Vilaseca notes that erda-iDRS Phase I trial focused on patients with papillary tumors relapsing after BCG, excluding those with carcinoma in situ (CIS), and suggests that the high concentration of erdafitinib in urine with minimal systemic absorption could offer significant benefits. This interview took place at the 41st Annual EAU Congress in London, UK.

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