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ASCO 2026 | Gender representation in Phase III solid tumor trials at ASCO 2015-2025

Sarbajit Mukherjee, MD, MS, Miami Cancer Institute, Miami, FL, discusses a cross-sectional analysis of Phase III solid tumor trial abstracts presented at the American Society of Clinical Oncology (ASCO) Annual Meeting from 2015 to 2025. The study evaluated gender representation among first and senior authors. While female authorship increased over the decade, women remained underrepresented overall and had lower odds of senior authorship. Disparities varied by tumor track and by geographic region, highlighting persistent structural gaps in academic oncology leadership. This interview took place during the 2026 ASCO Meeting in Chicago, IL.

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Transcript

We looked at the pattern of gender representation of all solid tumor phase 3 clinical trials presented at the ASCO annual meeting over a decade. The reason we wanted to look at it is there has been previous research that showed that female authors are typically underrepresented in large phase three clinical trials. What we didn’t know is if there has been a change in the trend...

We looked at the pattern of gender representation of all solid tumor phase 3 clinical trials presented at the ASCO annual meeting over a decade. The reason we wanted to look at it is there has been previous research that showed that female authors are typically underrepresented in large phase three clinical trials. What we didn’t know is if there has been a change in the trend. So we looked at the pattern of female authorship over a period of 10 years. And what we found was that firstly, female authors were underrepresented. The proportion of female authors was 28% over the whole study period. But interestingly, we saw that female authorship is increasing more recently. But what’s more interesting is we saw that this increase has not been uniform. We saw more increase in senior authorship compared to first authorship. We also saw significant variation based on the tumor tract as well as the geographic region of the female authors.

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