Sunandana Chandra, MD, MS, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, reviews data from a single-center Phase I/Ib study of concurrent intrathecal and intravenous nivolumab for patients with metastatic melanoma with leptomeningeal disease. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).