The 5th International Workshop on CAR-T (iwCAR-T) took place in Scottsdale, AZ, on 14 – 16 April, 2023, and brought together world-leading experts in CAR-T therapy as they discussed the latest in the field. In this podcast series, you will gain an insight into the sessions that took place at this year’s meeting, which covered the latest updates in CAR-T therapy in solid tumors, as well as associated challenges.

Today, experts Julian Molina (Mayo Clinic, Rochester, MN), Mathew Angelos (University of Pennsylvania, Philadelphia, PA), and Sebastian Kobold (Ludwig-Maximilians-University of Munich, Munich, Germany) bring you updates live from iwCART 2023. In considering the latest research and trials in the field of CAR T-cell therapy and the challenges associated with treating solid tumors, these specialists discuss using CAR macrophages in combination with other immunotherapies, manipulating the tumor microenvironment, the genetic engineering of CAR T-cells to add and/or remove specific factors, and tumor heterogeneity.