Even with aggressive surgical procedures, radiation therapy, and systemic chemotherapy, the outlook for individuals diagnosed with malignant brain tumors remains dismal, and conventional treatments come with notable risks of causing long-term cognitive impairments. There is a pressing and evident demand for the advancement of more efficient therapies that can complement standard approaches for invasive brain cancers while minimizing their harmful side effects. Cancer immunotherapy emerges as a hopeful treatment strategy capable of providing precise tumor-targeted cytotoxicity, offering the potential to eradicate brain tumor cells while preserving the delicate functions of the brain.

In this podcast we hear from Olivia Rongze Lu, PhD, University of California San Francisco, San Francisco, CA, Stephen Joseph Bagley, MD, MSCE, Hospital of the University of Pennsylvania, PA, Anthony Chalmers, MD, University of Glasgow, Glasgow, UK, and Philipp Karschnia, MD, Ludwig-Maximilians-University, Munich, Germany, as they discuss updates in immunotherapy for brain tumors.