Umberto Ricardi, MD, University of Turin, Turin, Italy, outlines the latest developments in radiotherapy for patients with lung cancer, highlighting the ability to improve treatment of brain metastases with radiosurgery, and novel hippocampal avoidance radiotherapy. Prof. Ricardi also discusses the potential role of proton therapy, hybrid machine learning, and immunotherapies. This video was recorded at the virtual European Lung Cancer Congress (ELCC) 2021.