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ESMO 2026 | Real-world first-line chemo-immunotherapy use in US and Korean BTC cases

Changhoon Yoo, MD, PhD, Asan Medical Center, Seoul, South Korea, provides an overview of a retrospective cohort study comparing real-world outcomes and post-progression treatment patterns in patients with advanced biliary tract cancer (aBTC) receiving first-line gemcitabine-platinum plus immune checkpoint inhibitors at US and Korean centers. Outcomes were broadly comparable, with differences in post-progression survival that may reflect variation in tumor subtype distribution and greater use of molecularly matched therapies after progression. This interview took place at the European Society for Medical Oncology (ESMO) 2026 Congress in Madrid, Spain.

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