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VJVirtual | EA5163/S1709/INSIGNA: the timing of pembrolizumab +/- chemo as 1L treatment and maintenance in NSCLC

Hossein Borghaei, DO, MS, Fox Chase Cancer Center, Philadelphia, PA, provides an overview of the Phase III EA5163/S1709 INSIGNA (NCT03793179) trial testing the timing of pembrolizumab alone or with chemotherapy as first-line treatment and maintenance in non-small cell lung cancer (NSCLC). Patients included have adenocarcinoma, PD-L1 expression of at least 1% and no driver mutations. The primary endpoint is overall-survival (OS) and secondary endpoints include progression-free survival (PFS), best objective response, PD-L1 positivity and safety. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).

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