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ESSO 44 | Bridging east–west disparities in gastric cancer surgical outcomes

Domenico D’Ugo, MD, Catholic University of Rome, Rome, Italy, discusses disparities in gastric cancer surgical treatment outcomes between Western and Eastern studies, highlighting significant differences in long-term survival rates for patients undergoing surgery alone. Prof. D’Ugo emphasizes the need to bridge the gap in surgical quality by implementing rigorous technique verification and evaluating oncological outcomes to achieve R0 resection, which involves the radical removal of local tumor involvement within the embryological block. This interview took place at the 44th Congress of the European Society of Surgical Oncology (ESSO 44) in Gothenburg, Sweden.

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Transcript

I’ve titled my presentation “The lesson of mesogastrium” because since always, the Western world has been following excellent results on hepatocellular carcinoma treatment by surgery alone that were obtained in the East by a number of different studies and trials. Still, comparing different arms of Western trials with Eastern trials, we can observe that the surgically alone arm demonstrates a huge difference with the same stage for long-term survival; this means the surgical quality in the West is still a gap, and this gap should be tried to be reduced by applying, you know, step-by-step verification of our technique and introducing textbook oncological outcome to the evaluation of our surgery before declaring it R0, particularly, according to my lecture, surgery is not just removing an organ with these lymph nodes, but any way of local involvement of the tumor should be radically removed inside the embryological block containing vessels, lymphatics, and diffusion of cells, that is called the metastatic root number five...

I’ve titled my presentation “The lesson of mesogastrium” because since always, the Western world has been following excellent results on hepatocellular carcinoma treatment by surgery alone that were obtained in the East by a number of different studies and trials. Still, comparing different arms of Western trials with Eastern trials, we can observe that the surgically alone arm demonstrates a huge difference with the same stage for long-term survival; this means the surgical quality in the West is still a gap, and this gap should be tried to be reduced by applying, you know, step-by-step verification of our technique and introducing textbook oncological outcome to the evaluation of our surgery before declaring it R0, particularly, according to my lecture, surgery is not just removing an organ with these lymph nodes, but any way of local involvement of the tumor should be radically removed inside the embryological block containing vessels, lymphatics, and diffusion of cells, that is called the metastatic root number five. If a tumor is still loco-regional and contained inside this embryological block, the surgery can be curative per se.

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