AACR 2023 | Targeted therapies in metastatic colorectal cancer

Benny Johnson, DO, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on the latest developments in using targeted therapies for patients with metastatic colorectal cancer. A full next-generation sequencing (NGS) panel is typically conducted, where BRAF, NRAS, KRAS, HER2 mutations, and the microsatellite status are all assessed. Whilst anti-EGFR antibodies are less efficacious in RAS-mutant colorectal cancer, bevacizumab, a VEGF inhibitor, is an option. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.

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