BTOG 2023 | TILs: Precision medicine in NSCLC

James Spicer, FCRP, PhD, MRCP, MBBS, King’s College London, London, UK, outlines the discussion around tumor infiltrating lymphocytes (TILs) at the British Thoracic Oncology Group (BTOG) Annual Conference 2023 as a novel precision therapy to treat NSCLC. Many TIL therapies are presently in trials, and Prof. Spicer specifically mentions the CHIRON study (NCT04032847) which is focused on advanced NSCLC. This trial selects TILs post-amplification that specifically target the neoantigens arising from genomic mutations in a given patient’s tumor. This interview took place at the BTOG Annual Conference 2023 in Belfast, UK.

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