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WCLC 2023 | Assessing I-SABR in early or recurrent non-small cell lung cancer

Joe Chang, MD, PhD, The University of Texas MD Anderson Cancer Centre, Houston, TX, shares the results of the Phase II trial (NCT03110978) of stereotactic ablative radiotherapy (SABR) combined with nivolumab, an immune checkpoint inhibitor, in early stage or recurrent isolated non-small cell lung cancer (NSCLC). The study demonstrated that multiple doses of nivolumab alongside SABR (I-SABR) significantly increased event-free survival, including a lower incidence of local, regional, distant or secondary malignancies. Dr Chang emphasises the importance of these results in demonstrating the effectiveness of immunotherapy in NSCLC. This interview took place at the 2023 World Conference on Lung Cancer (WCLC) in Singapore, Singapore.

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