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ESMO Breast 2024 | Second-line fulvestrant in pretreated metastatic invasive lobular carcinoma

Jason Mouabbi, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the efficacy of second-line fulvestrant in patients with metastatic invasive lobular carcinoma (mILC) following treatment with aromatase inhibitors (AI) and CDK4/6 inhibitors, based on an observational study. Fulvestrant was found to be ineffective, and no patients assessed continued on fulvestrant after a year. These findings highlight the need for new therapeutic strategies in pre-treated mILC. This interview took place at the 2024 European Society for Medical Oncology (ESMO) Breast Cancer Annual Congress in Berlin, Germany.

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