POUT is another UK National Cancer Research Institute trial. And this is a trial which we already know the primary results from. So, this was a trial of adjuvant chemotherapy in patients who’d undergone nephroureterectomy for T2 or above upper tract urothelial cancer. The primary end point of the trial was progression-free survival, and we already know that the trial had met that primary objective and was positive and so it’s already changed practice but this was the extended follow-up...
POUT is another UK National Cancer Research Institute trial. And this is a trial which we already know the primary results from. So, this was a trial of adjuvant chemotherapy in patients who’d undergone nephroureterectomy for T2 or above upper tract urothelial cancer. The primary end point of the trial was progression-free survival, and we already know that the trial had met that primary objective and was positive and so it’s already changed practice but this was the extended follow-up. In particular, we wanted to follow up the trial until we’d achieved a number of death events. Unfortunately, although there was a trend, there was no statistically significant overall survival gain with adjuvant chemotherapy in this context. It’s still a positive trial. This is a secondary end point and the primary end point findings were maintained in this study.