Chung Han-Lee, MD, PhD, Memorial Sloan Kettering Cancer Center, New York City, NY, USA, gives an overview of data coming from the phase II trial (NCT02501096) of lenvatinib plus pembrolizumab for disease progression after PD-1/PD-L1 immune checkpoint inhibitor in metastatic clear cell renal cell carcinoma. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).