Silke Gillessen, MD, PhD, University of Lugano, Lugano, Switzerland and the Oncology Institute of Southern Switzerland, Bellinzona, Switzerland, discusses the importance of patients in choosing a treatment for metastatic prostate cancer. Prof. Gillessen also discusses the use of geriatric assessment in clinical practice and the importance of biological age in the management of metastatic prostate cancer. This interview took place at the APCCC 2022 conference, held in Lugano, Switzerland.