Educational content on VJOncology is intended for healthcare professionals only. By visiting this website and accessing this information you confirm that you are a healthcare professional.

Share this video  

GU Cancers 2026 | Biomarker development and validation in prostate cancer research

Anna Wilkins, MD, PhD, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK, discusses the importance of careful development and extensive validation of biomarker tests for prostate cancer . High-quality clinical trial outcomes are crucial for maximizing the quality of validation work, particularly as seen in the CHHiP trial. This interview took place at the 2026 ASCO GU Cancers Symposium in San Francisco, CA.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Transcript

I think as really with any biomarker test, then careful development, but an extensive validation is key. And I think in the US, there has already been considerable training, testing and validation. But I think where we were excited about our work is that it was a very large external validation. And I think when you have well-powered, high-quality clinical trial outcomes with which to really test the model, then you maximize the quality of the validation work...

I think as really with any biomarker test, then careful development, but an extensive validation is key. And I think in the US, there has already been considerable training, testing and validation. But I think where we were excited about our work is that it was a very large external validation. And I think when you have well-powered, high-quality clinical trial outcomes with which to really test the model, then you maximize the quality of the validation work.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

Read more...