Michael Brian LaPelusa, MD, University of Texas MD Anderson Cancer Center, Houston, TX, comments on how circulating tumor DNA (ctDNA) can be used to evaluate the best course of treatment in patients with colorectal cancer. Numerous trials are assessing different checkpoint inhibitors over different timespans, and ctDNA with endoscopy can elucidate the appropriate length of treatment before surgery to spare patients from unnecessary treatment. Patients who have no ctDNA may additionally even be spared from surgery. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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