Srikala Sridhar, MD, FRCPC, of the Princess Margaret Cancer Centre, Toronto, ON, speaks on the treatment of high-risk localized prostate cancer. Speaking at the 2019 Genitourinary Cancers Symposium, held in San Francisco, CA, Dr Sridhar reports that a better characterization of biomarkers for early detection and as surrogate endpoints would significantly help obtain earlier readouts of drug efficacy during clinical trials.