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ESMO 2020 | Clinical trials in gynecological research: Ruby, NORA and IMagyn050

Mansoor Mirza, MD, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, discusses the clinical trials ongoing in gynecological research. For endometrial cancer, the Phase III Ruby (NCT03981796) trial is investigating the efficacy and safety of dostarlimab in combination with carboplatin-paclitaxel as well as the DUO-E trial (NCT04269200). For cervical cancer, a Phase II trial (NCT03438396) is evaluating the use of tisotumab vedotin in previously treated patients and planning a Phase III trial. Finally, in ovarian cancer, there is the Phase III NORA (NCT01847274) study and IMagyn050 (NCT03038100) trial. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).