David Chang, MBBS, FRACS, PhD, University of Glasgow, Glasgow, UK, shares his views on the role of whole-genome analysis in pancreatic cancer treatment at the ESMO 2020 education weekend. Dr Chang highlights the work done by the International Genome Consortium and the Cancer Genome Atlas, emphasizing how the rapid evolution of technical expertise in genome analysis over the past decade means the field is constantly developing and improving. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).