The updated results from the 12-year follow-up of the GETUG-12 (NCT00055731) study were presented at the European Society for Medical Oncology (ESMO) 2018 Congress, in Munich, Germany. Here, Alison Birtle, MD, of Royal Preston Hospital Lancashire Teaching Hospitals, Preston, UK, discusses this promising new data from the study, which investigated docetaxel and estramustine for high-risk localized prostate cancer. She highlights the fact that these data support that found in the UK-based STAMPEDE study (NCT00268476).