Sebastian Stintzing, MD, Charite University Hospital, Berlin, Germany, discusses the importance of liquid biopsy in combination tissue-based tests to detect RAS mutations in metastatic colorectal cancer (mCRC). Considering anti-EGFR only show efficacy in the RAS-wild type (WT) population, Prof. Stintzing emphasizes using liquid biopsy alongside a tissue test to reliably source out patients with RAS mutations who will not derive benefit form cetuximab or panitumumab. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.
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