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ESSO 45 | Mesenteric peritonectomy and cytoreductive surgery in peritoneal surface malignancies

Francesca Nava • 4 Nov 2026
ESSO 45
Gastrointestinal Cancer

Francesca Nava, MD, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, presents outcomes from a cohort analysis of mesenteric peritonectomy in peritoneal surface malignancies. Despite the added surgical burden when adding peritonectomy to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), the technique introduces no additional morbidity. The findings address a gap in the literature, as no prior outcome reports exist for this combined approach in clinical practice. This interview took place at the 2026 European Society of Surgical Oncology (ESSO) Annual Meeting in Madrid, Spain.

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Transcript

Well, we do believe it is always worth doing it when necessary...
Well, we do believe it is always worth doing it when necessary. So first of all, it’s important the assessment of the patient. And their needs. We do CT scans, which basically give an idea of the mesenteric involvement. And then after that, laparoscopy is suggested to check how the infiltration is actually perpetrated. Histology is a driver. It basically depends on the biological behavior of the illness. So, DMPMs and SPPCs are very good for this kind of procedure. PMPs are not very often needed. Because it does not infiltrate the peritoneum, whereas colon and gastric, they usually alter the architecture of the mesentery and it does make worth doing this procedure. Other than that, we do suggest integrating this technique in the common cytoreductive surgery techniques in order to give the patients the highest chances of a complete cytoreduction.

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The content of VJOncology is intended for healthcare professionals