FOOTPATH: NAPOLI versus sequential NAPOLI and mFOLFOX6 in mPDAC

Benedikt Westphalen, MD, PhD, Ludwig-Maximilians-University (LMU) Hospital, Munich, Germany, discusses the trial design of the Phase II FOOTPATH trial (NCT03487016), which compared gemcitabine with nab-paclitaxel, the NAPOLI regimen, and a sequence of NAPOLI and mFOLFOX6 in patients with metastatic pancreatic cancer (mPDAC). Despite the improvement in progression-free survival in patients receiving sequential therapy, it was not statistically significant. Safety was additionally improved in the sequential therapy arm. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.

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