Daniel A. Goldstein, MD, from Davidoff Cancer Center, Petah Tikva, Israel, describes the need for ensuring the cost-effectiveness of cancer care and explains that doctors should not be prescribing more drugs than that which is necessary to patients for achieving clinical benefit as the resources saved from doing this may be applied to other societal needs. This interview was filmed at the American Society of Oncology (ASCO) 2017 Annual Meeting in Chicago, IL.