Nishita Tripathi, MD, University of Utah, Salt Lake City, UT, outlines the results of a retrospective study evaluating the tumor genomic landscape in younger compared to older patients with metastatic clear cell renal cell carcinoma (mccRCC). No significant differences in the prevalence of targetable genomic aberrations, tumor mutational burden and frequency of genomic alterations in younger vs older pts with mccRCC. This interview took place at the American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium 2022 in San Francisco, CA.