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ESMO 2024 | NICHE-2: nivolumab and ipilimumab in non-metastatic MSI-high colon cancer

John Strickler, MD, Duke Cancer Institute, Durham, NC, gives an overview of the NICHE-2 trial (NCT03026140), which assessed immunotherapy for non-metastatic MSI-high colon cancer. Traditionally treated with resection and adjuvant chemotherapy, patients in the trial received nivolumab and ipilimumab. A promising 3-year disease-free survival rate was reported and the regimen was well-tolerated. The findings highlight the potential of the combination to become an emerging standard of care for this group of patients. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.

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