Yelena Janjigian, MD, Memorial Sloan Kettering Cancer Center, New York, NY, provides some background on the Phase III CheckMate 649 trial (NCT02872116) of nivolumab and chemotherapy or ipilimumab in the first line setting for patients with advanced gastric cancer/gastroesophageal junction cancer/esophageal adenocarcinoma (GC/GEJC/EAC). Whilst nivolumab with chemotherapy demonstrated survival benefit, addition of ipilimumab did not confer an overall survival advantage. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.
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