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ESMO 2025 | What is the optimal length of chemotherapy in pancreatic ductal adenocarcinoma?

Michele Reni, MD, IRCCS San Raffaele Scientific Institute, Milan, Italy, comments on the administration of chemotherapy in patients with pancreatic ductal adenocarcinoma (PDAC), recommending that they complete all six cycles if possible, with exceptions made for those experiencing toxicity, psychological fatigue, or other limitations. Dr Reni suggests that completing the full course of chemotherapy before surgery is ideal when feasible. This interview took place at the European Society for Medical Oncology (ESMO) 2025 Congress in Berlin, Germany.

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Transcript

Nowadays, what I advise, what I suggest to my patients is to continue, if possible, to receive all the six cycles. So we stop chemotherapy before six cycles in those patients who are unable to continue because of toxicity or because of psychological fatigue or for other reasons. But if we can, we continue the whole run of chemo before surgery.

This transcript is AI-generated...

Nowadays, what I advise, what I suggest to my patients is to continue, if possible, to receive all the six cycles. So we stop chemotherapy before six cycles in those patients who are unable to continue because of toxicity or because of psychological fatigue or for other reasons. But if we can, we continue the whole run of chemo before surgery.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

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