Lazar Popovic, MD, PhD, University of Novi Sad, Novi Sad, Serbia, highlights the importance of properly identifying and tailoring treatment to specific patients; for example, considering dose alterations in frail patients. Dr Popovic states it is necessary to educate clinicians so that they are able to diagnose and treat life-threatening toxicities early such as interstitial lung disease in trastuzumab deruxtecan treatment by performing routine low-dose CTs even in asymptomatic patients. He states that it is very important to only allow patients who are fit enough to undergo CAR-T and to hospitalize patients upon any signs of cytokine release syndrome. This interview took place at the European Society for Medical Oncology (ESMO) 2023 Congress in Madrid, Spain.
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