Wassim Kassouf, FRCS, MD, McGill University Health Centre, Montreal, Canada, discusses the combination of radiation with immune checkpoint inhibition in bladder cancer. Prof. Kassouf goes on to discuss BL13 (NCT03768570), an open-label randomized trial investigating trimodality therapy with or without durvalumab to treat patients with muscle-invasive bladder cancer. This interview took place at the 2020 Genitourinary Cancers Symposium, held in San Francisco, CA.