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AACR 2023 | Strategies to optimize Phase III combination immunotherapy trials

Thomas Urban Marron, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY, discusses issues in Phase III immunotherapy trials. Despite the success of immunotherapies such as TGF-β inhibitors and canakinumab, a novel IL-1β inhibitor, a number of therapies fail later stage trials due to the lack of suitable biomarkers. More thorough blood and biopsy analyses are needed to elucidate biomarkers. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.

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