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ASCO 2023 | What role does TIGIT inhibition have in treating hepatocellular carcinoma?

Ghassan Abou-Alfa, MD, MBA, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the latest updates in anti-TIGIT therapies for patients with hepatocellular carcinoma (HCC). Findings from the Phase Ib/II MORPHEUS-Liver trial (NCT04524871) of tiragolumab with atezolizumab and bevacizumab demonstrated the potential clinical benefit of adding tiragolumab, a TIGIT inhibitor. The Phase III IMbrave152/SKYSCRAPER-14 trial (NCT05904886) will further assess this combination. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.

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