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WCLC 2025 | NutriCare: nutritional support to optimize treatment intensity in NSCLC

Carolyn Presley, MD, The Ohio State University, Columbus, OH, comments on findings from the NutriCare study (NCT04986670), which evaluated medically tailored meals plus weekly nutritional counseling versus informational support in vulnerable patients with newly diagnosed lung cancer. Results showed that the intervention improved relative dose intensity among patients with stage IV non-small cell lung cancer (NSCLC), though participants also experienced a higher rate of grade 3 or higher adverse events, primarily gastrointestinal. This interview took place at 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.

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Transcript

Yeah, so the NutriCare study is actually one of the first studies in the United States to actually deliver food to patients’ homes as part of a nutritional intervention. And so in that randomized study, patients were either randomized just to nutritional information, which was NutriTool versus NutriCare, which was meals plus working with a registered dietitian. And we purposefully included participants who were either uninsured, older, in rural areas, or of underrepresented minorities...

Yeah, so the NutriCare study is actually one of the first studies in the United States to actually deliver food to patients’ homes as part of a nutritional intervention. And so in that randomized study, patients were either randomized just to nutritional information, which was NutriTool versus NutriCare, which was meals plus working with a registered dietitian. And we purposefully included participants who were either uninsured, older, in rural areas, or of underrepresented minorities. And we know that malnutrition is a huge issue, and we wanted to try and improve the nutritional content of both the food, but also access to food by sending it to their home rather than them having to leave their home to go get food and bring it home. So we were trying to, in a multifaceted approach, really decrease the barriers to healthy food. And so what we found is that we were able to, with the NutriCare group, we were able to actually deliver more cancer treatment in that group versus the NutriTool, just the nutritional information group. And so healthy nutrition, we think, is really important in helping our patients to get the cancer treatment as prescribed.

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