IASLC TTLC 2024 | Updates in the management of lung cancer with ADCs

Timothy Burns, MD, PhD, University of Pittsburgh & UPMC Hillman Cancer Center, Pittsburgh, PA, comments on the emerging role of antibody-drug conjugates (ADCs) in lung cancer. MET-targeting ADCs have been promising in patients with EGFR-mutant lung cancer as monotherapy or with existing tyrosine kinase inhibitors. Trastuzumab deruxtecan has additionally been approved in the second-line setting and trials are underway to assess the ADC in the first-line setting. Dr Burns also comments on datopotamab deruxtecan and sacituzumab govitecan. This interview took place at 2024 Targeted Therapies of Lung Cancer Meeting (TTLC 2024) in Santa Monica, CA.

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