Bora Lim, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, provides an outline of a talk at the San Antonio Breast Cancer Symposium (SABCS) 2020, where Dr Lim discussed novel targeted therapies in breast cancer, including those that act on the AKT-PI3K pathways, as evaluated in the IPATunity130 study (NCT03337724). This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).