Umberto Malapelle, PhD, University of Naples Federico II, Naples, Italy, discusses how to implement liquid biopsy into clinical practice and research. There are differences across the world in what types of liquid biopsy are used and how they are used. Dr Malapelle discusses some examples for how liquid biopsy is used in lung cancer. This interview took place at the International Society of Liquid Biopsy (ISLB) 2021 Virtual Meeting.