Nazli Dizman, MD, Yale University School of Medicine, New Haven, CT, provides an overview of CBM588, a strain of nonpathogenic bacteria that is a component of the gut microbiome. Given orally, it passes through the colon and produces short-chain fatty acids. CBM588 is associated with increased efficacy of immune checkpoint inhibitors in various cancer types. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.