Arpit Rao, MD, University of Minnesota, Minnesota, MN, talks on the clinical utility of liquid biopsies in prostate cancer, which represents a less invasive approach to identifying predictive and prognostic factors in patients with prostate cancer. Dr Rao also highlights the potential for prostate-specific exosomes that can recapitulate the transcriptome of prostate cancer cells. This interview took place at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021.