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ASCO 2026 | CRCI and compromised adjuvant chemotherapy delivery in cancer

Filippos Koinis, MD, PhD, University of Thessaly, Larissa, Greece, explores the association between early cancer-related cognitive impairment (CRCI) and chemotherapy treatment delivery outcomes in patients with early-stage breast cancer or colorectal cancer receiving adjuvant chemotherapy. Results demonstrated that early CRCI was significantly associated with reduced relative dose intensity, higher rates of treatment discontinuation, and increased treatment delays, identifying early CRCI as a clinically actionable target for risk-adapted supportive strategies to preserve curative-intent treatment delivery. This interview took place during the 2026 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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