Educational content on VJOncology is intended for healthcare professionals only. By visiting this website and accessing this information you confirm that you are a healthcare professional.

Share this video  

GU Cancers 2018 | TKI and checkpoint inhibitor combinations for kidney cancer: the IMmotion151 trial

The current standard of care for frontline kidney cancer is tyrosine kinase inhibitor (TKI) treatment. Now there are a host of promising immune checkpoint inhibitors in trials for this indication, either alone or in combination with TKIs. In this interview, Robert Jones, PhD, of the University of Glasgow & Beatson West of Scotland Cancer Centre, Glasgow, UK, discusses the Phase III randomized IMmotion151 trial of bevacizumab and atezolizumab vs. sunitinib for advanced renal cell carcinoma (NCT02420821). Prof. Jones discusses the rationale behind the combination, the trial cohort and the results thus far. He also mentions other up-and-coming checkpoint inhibitor-TKI combinations in trials. This video was recorded at the 2018 Genitourinary Cancers Symposium, held in San Francisco, CA.