Daniel Catenacci, MD, University of Chicago, Chicago, IL, discusses results from the MAHOGANY study, (NCT02318329) evaluating the use of margetuximab combined with anti-PD-1 (MGA012) or anti-PD-1/LAG-3 (MGD013) with or without chemotherapy in first-line therapy of advanced, metastatic HER2 positive gastroesophageal junction or gastric cancer. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).