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ESMO 2024 | Neo-CheckRay: safety findings of radiotherapy and immunotherapy in breast cancer

Alex De Caluwe, MD, Jules Bordet Institute, Brussels, Belgium, discusses safety findings from the Neo-CheckRay trial (NCT03875573), which combines radiotherapy and immunotherapy in luminal B breast cancer. The novel concurrent approach, typically delivered post-surgery, was safe, with no concerning safety signals. Radiotherapy was not shown to be toxic, with no grade 3 or 4 adverse events and only minimal grade 1 and 2 side effects. These outcomes support the trial’s progression, suggesting a well-tolerated treatment profile. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.

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