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ESMO 2022 | 7-year OS from SOLO1: sustained benefit with maintenance olaparib

Nicoletta Colombo, MD, PhD, Istituto Europeo di Oncologia, Milan, Italy, presents 7-year overall survival results from the Phase III SOLO1/GOG-3004 trial (NCT01844986) where it was demonstrated that maintenance olaparib provided sustained benefit beyond the end of treatment in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation. Following 7 years, 67.0% of olaparib patients vs 46.5% of placebo patients were alive and no new safety signals were detected. This, in combination with findings from PAOLA-1 (NCT02477644) supports the use of maintenance olaparib in this setting. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.

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