Gaia Griguolo, MD, University of Padova, Padova, Italy, talks on utilizing gene expression assays to aid in identifying subgroups of patients with HR-positive/HER2-negative breast cancer who have superior response rates to particular agents. Such assays could help to identify candidates for treatment in the neoadjuvant setting. This interview took place at the European Society for Medical Oncology (ESMO) Breast Cancer 2022 congress in Berlin, Germany.