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WCLC 2025 | THETIS: advancing thymic epithelial tumor management in Switzerland

Martina Imbimbo, MD, Ente Ospedaliero Cantonale, Lugano, Switzerland, gives an overview of the THETIS (THymic Cancers NETwork in Switzerland) network, a Swiss national initiative aimed at harmonizing care and advancing research for thymic epithelial tumors (TETs). Given the rarity and diagnostic challenges of TETs, the network provides multidisciplinary case discussions, expert pathology review, and the development of evidence-based treatment guidelines. A national registry integrating clinical, epidemiological, and biological data will support translational research and international collaboration, with the ultimate goal of improving diagnostic accuracy, treatment consistency, and patient outcomes. This interview took place at 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.

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Transcript

So, Switzerland is a small country, yet we have a lot of hospitals and it’s very, as other countries, so these are rare tumors, so it’s very easy that one center will see just two to three patients per year. So, you need really to team up to have more expertise. So, in other countries like Italy, like France, networks are already a reality even like a big country like France is centralizing all cases to be discussed with experts...

So, Switzerland is a small country, yet we have a lot of hospitals and it’s very, as other countries, so these are rare tumors, so it’s very easy that one center will see just two to three patients per year. So, you need really to team up to have more expertise. So, in other countries like Italy, like France, networks are already a reality even like a big country like France is centralizing all cases to be discussed with experts. So we’re trying to do the same thing. This is an inclusive network. It comprises 30 Swiss cities. It comprises a lot of different professionals. So we have oncologists, radio oncologists, surgeons, pathologists, neurologists, immunologists and the idea is to have national MDT for all cases so that we can discuss all the cases. After this we follow a registry to collect all this data and then generate real-world evidences on how timely tumors are treated in Switzerland and this will be benchmarked and in collaboration then with the international society so we can contribute then to worldwide research also funded by ISSC. And another thing that we are planning is a consensus conference to institute national guidelines because there are many gray areas also in ESMO guidelines and it’s very important that we discuss that in order to have an uniform standard of care.

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