Enrique Grande, MD, of the MD Anderson Cancer Center Madrid, Madrid, Spain, discusses the SUNEVO (GETNE-1408; NCT02402062) Phase II trial of sunitinib plus evofosfamide for G1/G2 metastatic pancreatic neuroendocrine tumors naïve for systemic treatment. While this failed to demonstrate activity in terms of tumor shrinkage, it revealed useful information. This interview took place at the European Society for Medical Oncology (ESMO) 2019 congress in Barcelona, Spain.