Icro Meattini, MD, University of Florence, Florence, Italy, discusses how the COVID-19 pandemic has impacted clinical practice in radiation therapy. Recent advances in radiation therapy have enabled clinicians to adapt to the pandemic, with trials such as FAST-Forward reporting useful data on how to improve radiation therapy schedules. Dr Meattini proposes that the pandemic has improved the speed of integration of precision medicine in radiation therapy. This interview took place at the San Antonio Breast Cancer Symposium 2021 in San Antonio.