This an exciting time for cancer research as recent breakthroughs are improving the landscape of cancer treatment. John Bell, PhD, from the University of Ottawa, Ottawa, Canada, presents an exciting oncolytic virus approach to treating cancer being investigated in trials. Dr Bell speaks at the 2018 National Cancer Research Institute (NCRI) Cancer Conference, held in Glasgow, UK on oncolytic viruses, their potential applications, benefits, challenges, and implications in cancer treatment.